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Posted May 4, 2026Back to blogs
Written by: Jenn Fernandez
Reviewed By: Dr. Joel Evans
If you are a woman over 35 thinking about preconception, don’t let the misconceptions about reproductive wellness get in your way. While many women start their preconception journey in their 20s and early 30s, you might be starting in your mid-to-late 30s, which is still a great time to embark on this journey.
Reproductive health involves many factors, but cellular wellness is one key factor in the preconception process. The health of your mitochondria (the energy-producing part of the cell) influence how reproductive systems and cells (like eggs) function — especially as you age. This blog gives you the knowledge to prepare for preconception in your mid-to-late 30s, insight into how Kaneka Ubiquinol® can support preconception, and lifestyle habits to promote your reproductive health.
Aging is a natural part of life, and it also brings biological changes that can impact women’s reproductive health. Peak fertility does decrease with age, but despite what you may have heard, opportunities to conceive don’t just stop at a certain age. In fact, women over 35 account for 20% of all births. Understanding how cellular health and egg quality change for women over 35 helps you make informed decisions so you can optimize your preconception journey.
A key player in both reproductive wellness and overall health is ubiquinol: the active antioxidant form of CoQ10 (the main fuel for your mitochondria to produce energy). Ubiquinol is just one piece of the complex reproductive health puzzle, but understanding its role in cellular energy production and antioxidant protection can help support your preconception journey.
Ubiquinol supports the production of cellular energy that fuels your body and powers your cells — including your reproductive cells. As we age, this process becomes less efficient. Aging is also associated with increased cellular damage, including to reproductive cells, caused by reactive oxygen species (ROS). These molecules are produced both inside the body and arise from exposure to environmental sources, such as smoke, car exhaust, and toxic chemicals — leading to what’s called “oxidative stress.”
Oxidative stress is an imbalance between free radicals and antioxidants, with the free radicals being in excess. Over time, this imbalance can lead to cell and tissue damage. For women, it can impair oocyte and egg quality by damaging DNA, proteins, and cell membranes, hindering proper maturation and function.1 For men, it can impair reproductive health as well.2
Read More: Explore the Role of Antioxidants on Preconception
Because women are born with a limited number of oocytes (or egg cells) and don’t create new ones over time, protecting reproductive cells becomes an important part of supporting reproductive health.3 But how does one do that in the face of aging?
In order to really understand the impact of aging on your preconception journey as you age, we must first talk about oocyte and egg quality. Oocytes are egg cells that have not fully matured, a stage that lasts from birth until shortly before ovulation. Oocyte and egg quality depend on their chromosomal integrity, cellular health, and energy capacity — all of which are impacted by various factors, including a woman’s age, health status, oxidative balance, lifestyle, and environmental conditions.4
Like other cells, oocytes rely on cellular energy to function, and the body’s process of generating ubiquinol is key to energy production. Oocytes contain the greatest number of mitochondria in any cell, given their high cellular energy demands as they mature and develop into an egg.5 As we age, however, mitochondrial health can decline: fewer new mitochondria are produced, there’s an increase in mitochondrial self-destruction (apoptosis), and cell membranes can become altered, increasing oxidative stress.6 These changes are known to impact oocyte quality, which is why supporting mitochondrial function is important for healthy eggs.
Embarking on your preconception journey can feel overwhelming, but Kaneka Ubiquinol® is your wellness ally that promotes cellular wellness and supports preconception health and a number of other health goals.
It offers antioxidant protection that supports cellular health as we age, helping to neutralize free radicals and protect cells from oxidative stress. This is particularly helpful for women in their mid-to-late 30s on their preconception journey, given the biological changes at this age. Backed by years of research and rigorous testing, this supplement is one both men and women can trust during all stages of life. Talk to your healthcare provider specializing in reproductive wellness about a Kaneka Ubiquinol® supplement.
Read More: Discover Who We Are
When it comes to reproductive health, there’s no substitute for healthy lifestyle choices and a holistic approach to wellness. Maintaining the healthy habits listed below plays a key role in promoting reproductive health for women and men in their 20s and 30s:
For most women and men, focusing on preconception health doesn’t have to mean an overhaul of your entire life. Start with simple changes that you can stick to daily, and build on those to make a meaningful difference over time.
Read More: When to Start Taking Kaneka Ubiquinol® for Preconception Wellness
Starting your preconception journey in your mid-30s is not unusual, but it does mean you should think differently about your nutritional needs as you focus on how to best support your cellular and overall health. If you’re wondering how to begin, start with the following steps:
You have the knowledge to take control of your preconception health, and Kaneka Ubiquinol® is ready to support you along the way, in your 30s and beyond.
Read More: Review Our Comprehensive Guide to Preparing for Conception
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1 Kirillova A, Smitz JEJ, Sukhikh GT, Mazunin I. The role of mitochondria in oocyte maturation. Cells. 2021 Sep 19;10(9):2484.
2 https://www.mdpi.com/2076-3921/9/4/287?utm
3 Bastawros H. Human Reproduction: A Clinical Approach. 2023, Iowa State University Digital Press. pp. 10.
4 Mihalas BP, Redgrove KA, McLaughlin EA, Nixon B. Molecular mechanisms responsible for increased vulnerability of the ageing oocyte to oxidative damage. Oxid Med Cell Longev. 2017;2017:4015874.
5 Bentov Y, Casper RF. The aging oocyte–can mitochondrial function be improved? Fertil Steril. 2013 Jan;99(1):18-22.
6 Zhu Z, Xu W, Liu L. Ovarian aging: mechanisms and intervention strategies. Medical Review 2022 Nov;2(6):590–610.
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April 11, 2025 · Heather Eberly
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